Regulatory T cells promote myelin regeneration in the Central Nervous System

Regeneration of central nervous system (CNS) myelin involves differentiation of oligodendrocytes from oligodendrocyte progenitor cells (OPC). In multiple sclerosis (MS), remyelination can fail despite abundant OPC, suggesting impairment of oligodendrocyte differentiation. T cells infiltrate the CNS...

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Publicat a:Nat Neurosci
Autors principals: Dombrowski, Yvonne, O’Hagan, Thomas, Dittmer, Marie, Penalva, Rosana, Mayoral, Sonia R., Bankhead, Peter, Fleville, Samara, Eleftheriadis, George, Zhao, Chao, Naughton, Michelle, Hassan, Rachel, Moffat, Jill, Falconer, John, Boyd, Amanda, Hamilton, Peter, Allen, Ingrid V., Kissenpfennig, Adrien, Moynagh, Paul N., Evergren, Emma, Perbal, Bernard, Williams, Anna C., Ingram, Rebecca J., Chan, Jonah R., Franklin, Robin J.M., Fitzgerald, Denise C.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409501/
https://ncbi.nlm.nih.gov/pubmed/28288125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4528
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