Regulatory T cells promote myelin regeneration in the Central Nervous System

Regeneration of central nervous system (CNS) myelin involves differentiation of oligodendrocytes from oligodendrocyte progenitor cells (OPC). In multiple sclerosis (MS), remyelination can fail despite abundant OPC, suggesting impairment of oligodendrocyte differentiation. T cells infiltrate the CNS...

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Publicado no:Nat Neurosci
Main Authors: Dombrowski, Yvonne, O’Hagan, Thomas, Dittmer, Marie, Penalva, Rosana, Mayoral, Sonia R., Bankhead, Peter, Fleville, Samara, Eleftheriadis, George, Zhao, Chao, Naughton, Michelle, Hassan, Rachel, Moffat, Jill, Falconer, John, Boyd, Amanda, Hamilton, Peter, Allen, Ingrid V., Kissenpfennig, Adrien, Moynagh, Paul N., Evergren, Emma, Perbal, Bernard, Williams, Anna C., Ingram, Rebecca J., Chan, Jonah R., Franklin, Robin J.M., Fitzgerald, Denise C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409501/
https://ncbi.nlm.nih.gov/pubmed/28288125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4528
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