The GPRC6A receptor displays constitutive internalization and sorting to the slow recycling pathway

The class C G protein-coupled receptor GPRC6A is a putative nutrient-sensing receptor and represents a possible new drug target in metabolic disorders. However, the specific physiological role of this receptor has yet to be identified, and the mechanisms regulating its activity and cell surface avai...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Jacobsen, Stine Engesgaard, Ammendrup-Johnsen, Ina, Jansen, Anna Mai, Gether, Ulrik, Madsen, Kenneth Lindegaard, Bräuner-Osborne, Hans
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409461/
https://ncbi.nlm.nih.gov/pubmed/28280242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.762385
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