Modeling Ovarian Cancer Multicellular Spheroid Behavior in a Dynamic 3D Peritoneal Microdevice

Ovarian cancer is characterized by extensive peritoneal metastasis, with tumor spheres commonly found in the malignant ascites. This is associated with poor clinical outcomes and currently lacks effective treatment. Both the three-dimensional (3D) environment and the dynamic mechanical forces are ve...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Li, Shan-Shan, Ip, Carman K. M., Tang, Matthew Y. H., Sy, Samuel K. H., Yung, Susan, Chan, Tak-Mao, Yang, Mengsu, Shum, Ho Cheung, Wong, Alice S.T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2017
Soggetti:
Bioengineering
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409276/
https://ncbi.nlm.nih.gov/pubmed/28287578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55337
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