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p70 S6 kinase drives ovarian cancer metastasis through multicellular spheroid-peritoneum interaction and P-cadherin/β1 integrin signaling activation

Peritoneal dissemination as a manifestation of ovarian cancer is an adverse prognostic factor associated with poor clinical outcome, and is thus a potentially promising target for improved treatment. Sphere forming cells (multicellular spheroids) present in malignant ascites of patients with ovarian...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Man Ip, Carman Ka, Yung, Susan, Chan, Tak-Mao, Tsao, Sai-Wah, Tsai Wong, Alice Sze
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253424/
https://ncbi.nlm.nih.gov/pubmed/25193855
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