Modeling Ovarian Cancer Multicellular Spheroid Behavior in a Dynamic 3D Peritoneal Microdevice

Ovarian cancer is characterized by extensive peritoneal metastasis, with tumor spheres commonly found in the malignant ascites. This is associated with poor clinical outcomes and currently lacks effective treatment. Both the three-dimensional (3D) environment and the dynamic mechanical forces are ve...

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Li, Shan-Shan, Ip, Carman K. M., Tang, Matthew Y. H., Sy, Samuel K. H., Yung, Susan, Chan, Tak-Mao, Yang, Mengsu, Shum, Ho Cheung, Wong, Alice S.T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2017
Schlagworte:
Bioengineering
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409276/
https://ncbi.nlm.nih.gov/pubmed/28287578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55337
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