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Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4
D4Z4 repeats are present in at least 11 different mammalian species, including humans and mice. Each repeat contains an open reading frame encoding a double homeodomain (DUX) family transcription factor. Aberrant expression of the D4Z4 ORF called DUX4 is associated with the pathogenesis of Facioscap...
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| Publicado no: | Hum Mol Genet |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5409219/ https://ncbi.nlm.nih.gov/pubmed/28173143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw287 |
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