Megakaryocytes compensate for Kit insufficiency in murine arthritis

The growth factor receptor Kit is involved in hematopoietic and nonhematopoietic development. Mice bearing Kit defects lack mast cells; however, strains bearing different Kit alleles exhibit diverse phenotypes. Herein, we investigated factors underlying differential sensitivity to IgG-mediated arthr...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Cunin, Pierre, Penke, Loka R., Thon, Jonathan N., Monach, Paul A., Jones, Tatiana, Chang, Margaret H., Chen, Mary M., Melki, Imene, Lacroix, Steve, Iwakura, Yoichiro, Ware, Jerry, Gurish, Michael F., Italiano, Joseph E., Boilard, Eric, Nigrovic, Peter A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409069/
https://ncbi.nlm.nih.gov/pubmed/28375155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84598
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