Megakaryocytes compensate for Kit insufficiency in murine arthritis

The growth factor receptor Kit is involved in hematopoietic and nonhematopoietic development. Mice bearing Kit defects lack mast cells; however, strains bearing different Kit alleles exhibit diverse phenotypes. Herein, we investigated factors underlying differential sensitivity to IgG-mediated arthr...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Cunin, Pierre, Penke, Loka R., Thon, Jonathan N., Monach, Paul A., Jones, Tatiana, Chang, Margaret H., Chen, Mary M., Melki, Imene, Lacroix, Steve, Iwakura, Yoichiro, Ware, Jerry, Gurish, Michael F., Italiano, Joseph E., Boilard, Eric, Nigrovic, Peter A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409069/
https://ncbi.nlm.nih.gov/pubmed/28375155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84598
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