Megakaryocytes compensate for Kit insufficiency in murine arthritis

The growth factor receptor Kit is involved in hematopoietic and nonhematopoietic development. Mice bearing Kit defects lack mast cells; however, strains bearing different Kit alleles exhibit diverse phenotypes. Herein, we investigated factors underlying differential sensitivity to IgG-mediated arthr...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Cunin, Pierre, Penke, Loka R., Thon, Jonathan N., Monach, Paul A., Jones, Tatiana, Chang, Margaret H., Chen, Mary M., Melki, Imene, Lacroix, Steve, Iwakura, Yoichiro, Ware, Jerry, Gurish, Michael F., Italiano, Joseph E., Boilard, Eric, Nigrovic, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409069/
https://ncbi.nlm.nih.gov/pubmed/28375155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84598
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