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PD-L1 serves as a double agent in separating GVL from GVHD

Allogeneic hematopoietic cell transplantation (HCT) represents a potentially curative treatment for a variety of hematologic malignancies due to the well-recognized graft-versus-leukemia/lymphoma (GVL) effect that is mediated by donor-derived alloreactive T cells. However, graft-versus-host disease...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Brennan, Todd V., Yang, Yiping
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409065/
https://ncbi.nlm.nih.gov/pubmed/28414300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94196
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