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Analysis of Termination of Transcription Using BrUTP-strand-specific Transcription Run-on (TRO) Approach

This manuscript describes a protocol for detecting transcription termination defect in vivo. The strand-specific TRO protocol using BrUTP described here is a powerful experimental approach for analyzing the transcription termination defect under physiological conditions. Like the traditional TRO ass...

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Détails bibliographiques
Publié dans:J Vis Exp
Auteurs principaux: Dhoondia, Zuzer, Tarockoff, Ricci, Alhusini, Nadra, Medler, Scott, Agarwal, Neha, Ansari, Athar
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408991/
https://ncbi.nlm.nih.gov/pubmed/28362387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55446
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