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Regulated Formation of LncRNA-DNA Hybrids Enables Faster Transcriptional Induction and Environmental Adaptation

Long non-coding (lnc)RNAs, once thought to merely represent noise from imprecise transcription initiation, have now emerged as major regulatory entities in all eukaryotes. In contrast to the rapidly expanding identification of individual lncRNAs, mechanistic characterization has lagged behind. Here...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell
Hauptverfasser: Cloutier, Sara C., Wang, Siwen, Ma, Wai Kit, Al Husini, Nadra, Dhoondia, Zuzer, Ansari, Athar, Pascuzzi, Pete E., Tran, Elizabeth J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744127/
https://ncbi.nlm.nih.gov/pubmed/26833086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.12.024
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