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Regulated Formation of LncRNA-DNA Hybrids Enables Faster Transcriptional Induction and Environmental Adaptation

Long non-coding (lnc)RNAs, once thought to merely represent noise from imprecise transcription initiation, have now emerged as major regulatory entities in all eukaryotes. In contrast to the rapidly expanding identification of individual lncRNAs, mechanistic characterization has lagged behind. Here...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Cloutier, Sara C., Wang, Siwen, Ma, Wai Kit, Al Husini, Nadra, Dhoondia, Zuzer, Ansari, Athar, Pascuzzi, Pete E., Tran, Elizabeth J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744127/
https://ncbi.nlm.nih.gov/pubmed/26833086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.12.024
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