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Remarkably Facile Borane-Promoted, Rhodium-Catalyzed Asymmetric Hydrogenation of Tri- and Tetrasubstituted Alkenes

[Image: see text] Oxime-directed catalytic asymmetric hydroboration is diverted to catalytic asymmetric hydrogenation (CAH) upon the addition of a proton source, such as MeOH, or by running the reaction under a hydrogen atmosphere. A borane (e.g., pinacolborane) is required to promote CAH. Tri- and...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Shoba, Veronika M., Takacs, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408738/
https://ncbi.nlm.nih.gov/pubmed/28394591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b02581
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