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Effect of APOL1 disease risk variants on APOL1 gene product
Gene sequence mutations may alter mRNA transcription, transcript stability, protein translation, protein stability and protein folding. Apolipoprotein L1 (APOL1) has two sets of sequence variants that are risk factors for kidney disease development, APOL1G1 (substitution mutation) and APOL1G2 (delet...
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| Pubblicato in: | Biosci Rep |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408699/ https://ncbi.nlm.nih.gov/pubmed/28385815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160531 |
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