Long‐term miR‐29b suppression reduces aneurysm formation in a Marfan mouse model

Aortic root aneurysm formation and subsequent dissection and/or rupture remain the leading cause of death in patients with Marfan syndrome. Our laboratory has reported that miR‐29b participates in aortic root/ascending aorta extracellular matrix remodeling during early aneurysm formation in Fbn1 (C1...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Okamura, Homare, Emrich, Fabian, Trojan, Jeffrey, Chiu, Peter, Dalal, Alex R., Arakawa, Mamoru, Sato, Tetsuya, Penov, Kiril, Koyano, Tiffany, Pedroza, Albert, Connolly, Andrew J., Rabinovitch, Marlene, Alvira, Cristina, Fischbein, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408287/
https://ncbi.nlm.nih.gov/pubmed/28455451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13257
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