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Heterogeneous Dielectric Generalized Born model with a van der Waals Term (HDGBvdW) Provides Improved Association Energetics of Membrane-Embedded Transmembrane Helices

The Heterogeneous Dielectric Generalized Born (HDGB) implicit membrane formalism is extended by the addition of a van der Waals dispersion term to better describe the nonpolar components of the free energy of solvation. The new model, termed HDGBvdW, improves the energy estimates in the hydrophobic...

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Detalhes bibliográficos
Publicado no:J Comput Chem
Main Authors: Dutagaci, Bercem, Sayadi, Maryam, Feig, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407934/
https://ncbi.nlm.nih.gov/pubmed/28160300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.24691
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