GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome

Upon viral infection, retinoic acid–inducible gene I–like receptors (RLRs) recognize viral RNA and trigger a series of signaling events, leading to the induction of type I interferons (IFNs). These processes are delicately regulated to prevent excessive and harmful immune responses. In this study, w...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Nie, Ying, Ran, Yong, Zhang, Hong-Yan, Huang, Zhe-Fu, Pan, Zhao-Yi, Wang, Su-Yun, Wang, Yan-Yi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407853/
https://ncbi.nlm.nih.gov/pubmed/28414768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006328
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