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Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis

BACKGROUND: A host defense function for Alkaline phosphatases (ALPs) is suggested by the contribution of intestinal ALP to detoxifying bacterial lipopolysaccharide (endotoxin) in animal models in vivo and the elevation of ALP activity following treatment of human cells with inflammatory stimuli in v...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Pettengill, Matthew, Matute, Juan D., Tresenriter, Megan, Hibbert, Julie, Burgner, David, Richmond, Peter, Luis Millán, José, Ozonoff, Al, Strunk, Tobias, Currie, Andrew, Levy, Ofer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407836/
https://ncbi.nlm.nih.gov/pubmed/28448526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175936
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