Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis

BACKGROUND: A host defense function for Alkaline phosphatases (ALPs) is suggested by the contribution of intestinal ALP to detoxifying bacterial lipopolysaccharide (endotoxin) in animal models in vivo and the elevation of ALP activity following treatment of human cells with inflammatory stimuli in v...

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Publicado en:PLoS One
Autores principales: Pettengill, Matthew, Matute, Juan D., Tresenriter, Megan, Hibbert, Julie, Burgner, David, Richmond, Peter, Luis Millán, José, Ozonoff, Al, Strunk, Tobias, Currie, Andrew, Levy, Ofer
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407836/
https://ncbi.nlm.nih.gov/pubmed/28448526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175936
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