Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI

Overexpression of the proximal tubular enzyme myo-inositol oxygenase (MIOX) induces oxidant stress in vitro. However, the relevance of MIOX to tubular pathobiology remains enigmatic. To investigate the role of MIOX in cisplatin-induced tubular AKI, we generated conditional MIOX-overexpressing transg...

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Bibliografiset tiedot
Julkaisussa:J Am Soc Nephrol
Päätekijät: Dutta, Rajesh K., Kondeti, Vinay K., Sharma, Isha, Chandel, Navdeep S., Quaggin, Susan E., Kanwar, Yashpal S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2017
Aiheet:
Basic Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407728/
https://ncbi.nlm.nih.gov/pubmed/27895157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016070744
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