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Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors

Obesity is associated with perturbations in cellular energy homeostasis and consequential renal injury leading to chronic renal disease (CKD). Myo-inositol oxygenase (MIOX), a tubular enzyme, alters redox balance and subsequent tubular injury in the settings of obesity. Mechanism(s) for such adverse...

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Bibliografiske detaljer
Udgivet i:Biomedicines
Main Authors: Sharma, Isha, Deng, Fei, Kanwar, Yashpal S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400661/
https://ncbi.nlm.nih.gov/pubmed/32708636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8070217
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