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Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI
Overexpression of the proximal tubular enzyme myo-inositol oxygenase (MIOX) induces oxidant stress in vitro. However, the relevance of MIOX to tubular pathobiology remains enigmatic. To investigate the role of MIOX in cisplatin-induced tubular AKI, we generated conditional MIOX-overexpressing transg...
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Publicado no: | J Am Soc Nephrol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Nephrology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407728/ https://ncbi.nlm.nih.gov/pubmed/27895157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016070744 |
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