Prostanoid-dependent spontaneous pain and PAR(2)-dependent mechanical allodynia following oral mucosal trauma: Involvement of TRPV1, TRPA1, and TRPV4

During dental treatments, intraoral appliances frequently induce traumatic ulcers in the oral mucosa. Such mucosal injury-induced mucositis leads to severe pain, resulting in poor quality of life and decreased cooperation in the therapy. To elucidate mucosal pain mechanisms, we developed a new rat m...

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Vydáno v:Mol Pain
Hlavní autoři: Ito, Misa, Ono, Kentaro, Hitomi, Suzuro, Nodai, Tomotaka, Sago, Teppei, Yamaguchi, Kiichiro, Harano, Nozomu, Gunjigake, Kaori, Hosokawa, Ryuji, Kawamoto, Tatsuo, Inenaga, Kiyotoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407658/
https://ncbi.nlm.nih.gov/pubmed/28381109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806917704138
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