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Spinal NKCC1 blockade inhibits TRPV1-dependent referred allodynia
BACKGROUND: The Na(+), K(+), 2Cl(- )type I cotransporter (NKCC1) and TRPV1 receptors, at the level of the dorsal horn, have been implicated in mediating allodynia in response to an inflammatory insult. The NKCC1 cotransporter regulates intracellular [Cl(-)] and thus the magnitude and polarity of GAB...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1929059/ https://ncbi.nlm.nih.gov/pubmed/17603899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-3-17 |
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