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Thermal Hyperalgesia and Mechanical Allodynia Elicited by Histamine and Non-histaminergic Itch Mediators: Respective Involvement of TRPV1 and TRPA1
Acute itch is elicited by histamine, as well as non-histaminergic itch mediators including chloroquine, BAM8–22 and Ser-Leu-Ile-Gly-Arg-Leu (SLIGRL). When injected intradermally, histamine binds to histamine H1 and H4 receptors that activate transient receptor potential vanilloid 1 (TRPV1) to depola...
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| Publicado no: | Neuroscience |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8219216/ https://ncbi.nlm.nih.gov/pubmed/33010342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2020.09.048 |
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