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Deficiency of α7 Nicotinic Acetylcholine Receptor Attenuates Bleomycin-Induced Lung Fibrosis in Mice

α7 nicotinic acetylcholine receptor (α7 nAChR, coded by Chrna7) is indispensable in dampening proinflammatory responses. However, whether α7 nAChR plays a role in regulating bleomycin (BLM)-induced lung fibrosis is less investigated. Here, we challenged wild-type and Chrna7(-/-) mice with BLM intrat...

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Bibliografiska uppgifter
I publikationen:Mol Med
Huvudupphovsmän: Sun, Peiyu, Li, Ling, Zhao, Caiqi, Pan, Mengyao, Qian, Zhikang, Su, Xiao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Feinstein Institute for Medical Research 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407281/
https://ncbi.nlm.nih.gov/pubmed/28283678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00083
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