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Deficiency of α7 Nicotinic Acetylcholine Receptor Attenuates Bleomycin-Induced Lung Fibrosis in Mice
α7 nicotinic acetylcholine receptor (α7 nAChR, coded by Chrna7) is indispensable in dampening proinflammatory responses. However, whether α7 nAChR plays a role in regulating bleomycin (BLM)-induced lung fibrosis is less investigated. Here, we challenged wild-type and Chrna7(-/-) mice with BLM intrat...
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| Veröffentlicht in: | Mol Med |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Feinstein Institute for Medical Research
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407281/ https://ncbi.nlm.nih.gov/pubmed/28283678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00083 |
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