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Hypoxia induces arginase II expression and increases viable human pulmonary artery smooth muscle cell numbers via AMPKα(1) signaling
Pulmonary artery smooth muscle cell (PASMC) proliferation is one of the hallmark features of hypoxia-induced pulmonary hypertension. With only supportive treatment options available for this life-threatening disease, treating and preventing the proliferation of PASMCs is a viable therapeutic option....
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| Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407096/ https://ncbi.nlm.nih.gov/pubmed/28213467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00117.2016 |
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