Primary cilia regulate the osmotic stress response of renal epithelial cells through TRPM3

Primary cilia sense environmental conditions, including osmolality, but whether cilia participate in the osmotic response in renal epithelial cells is not known. The transient receptor potential (TRP) channels TRPV4 and TRPM3 are osmoresponsive. TRPV4 localizes to cilia in certain cell types, while...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Siroky, Brian J., Kleene, Nancy K., Kleene, Steven J., Varnell, Charles D., Comer, Raven G., Liu, Jialiu, Lu, Lu, Pachciarz, Nolan W., Bissler, John J., Dixon, Bradley P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407065/
https://ncbi.nlm.nih.gov/pubmed/28122715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00465.2015
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