Primary cilia regulate the osmotic stress response of renal epithelial cells through TRPM3

Primary cilia sense environmental conditions, including osmolality, but whether cilia participate in the osmotic response in renal epithelial cells is not known. The transient receptor potential (TRP) channels TRPV4 and TRPM3 are osmoresponsive. TRPV4 localizes to cilia in certain cell types, while...

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Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Siroky, Brian J., Kleene, Nancy K., Kleene, Steven J., Varnell, Charles D., Comer, Raven G., Liu, Jialiu, Lu, Lu, Pachciarz, Nolan W., Bissler, John J., Dixon, Bradley P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407065/
https://ncbi.nlm.nih.gov/pubmed/28122715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00465.2015
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