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Triglyceride-rich lipoprotein lipolysis products increase blood-brain barrier transfer coefficient and induce astrocyte lipid droplets and cell stress

Elevation of blood triglycerides, primarily as triglyceride-rich lipoproteins (TGRL), has been linked to cerebrovascular inflammation, vascular dementia, and Alzheimer’s disease (AD). Brain microvascular endothelial cells and astrocytes, two cell components of the neurovascular unit, participate in...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Lee, Linda L., Aung, Hnin H., Wilson, Dennis W., Anderson, Steven E., Rutledge, John C., Rutkowsky, Jennifer M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407020/
https://ncbi.nlm.nih.gov/pubmed/28077357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00120.2016
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