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Induction of ATF3 Gene Network by Triglyceride-Rich Lipoprotein Lipolysis Products Increases Vascular Apoptosis and Inflammation

OBJECTIVE: Elevation of triglyceride-rich lipoproteins (TGRL) contributes to the risk for atherosclerotic cardiovascular disease (ASCVD). Our work has shown that TGRL lipolysis products in high physiological to pathophysiological concentrations cause endothelial cell injury; however, the mechanisms...

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Detalhes bibliográficos
Main Authors: Aung, Hnin H., Lamé, Michael W., Gohil, Kishorchandra, An, Chung-Il, Wilson, Dennis W., Rutledge, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921073/
https://ncbi.nlm.nih.gov/pubmed/23868936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.301375
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