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Triglyceride-rich lipoprotein lipolysis products increase blood-brain barrier transfer coefficient and induce astrocyte lipid droplets and cell stress
Elevation of blood triglycerides, primarily as triglyceride-rich lipoproteins (TGRL), has been linked to cerebrovascular inflammation, vascular dementia, and Alzheimer’s disease (AD). Brain microvascular endothelial cells and astrocytes, two cell components of the neurovascular unit, participate in...
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Publicat a: | Am J Physiol Cell Physiol |
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Autors principals: | , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Physiological Society
2017
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407020/ https://ncbi.nlm.nih.gov/pubmed/28077357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00120.2016 |
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