LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State

The low-density lipoprotein receptor-related protein 1, LRP1, interacts with APP and affects its processing. This is assumed to be mostly caused by the impact of LRP1 on APP endocytosis. More recently, also an interaction of APP and LRP1 early in the secretory pathway was reported whereat retention...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Herr, Uta-Mareike, Strecker, Paul, Storck, Steffen E., Thomas, Carolin, Rabiej, Verena, Junker, Anne, Schilling, Sandra, Schmidt, Nadine, Dowds, C. Marie, Eggert, Simone, Pietrzik, Claus U., Kins, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406469/
https://ncbi.nlm.nih.gov/pubmed/28496400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00118
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