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Structural aspects and physiological consequences of APP/APLP trans-dimerization
The amyloid precursor protein (APP) is one of the key proteins in Alzheimer’s disease (AD), as it is the precursor of amyloid β (Aβ) peptides accumulating in amyloid plaques. The processing of APP and the pathogenic features of especially Aβ oligomers have been analyzed in detail. Remarkably, there...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308009/ https://ncbi.nlm.nih.gov/pubmed/21952790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00221-011-2878-6 |
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