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Signal transduction pathways activated by insulin‐like peptide 5 at the relaxin family peptide RXFP4 receptor

BACKGROUND AND PURPOSE: Insulin‐like peptide 5 (INSL5) is a two‐chain, three‐disulfide‐bonded peptide of the insulin/relaxin superfamily, uniquely expressed in enteroendocrine l‐cells of the colon. It is the cognate ligand of relaxin family peptide RXFP4 receptor that is mainly expressed in the colo...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Ang, Sheng Y, Hutchinson, Dana S, Patil, Nitin, Evans, Bronwyn A, Bathgate, Ross A D, Halls, Michelle L, Hossain, Mohammed A, Summers, Roger J, Kocan, Martina
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406383/
https://ncbi.nlm.nih.gov/pubmed/27243554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13522
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