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Directional Force Originating from ATP Hydrolysis Drives the GroEL Conformational Change

Protein functional mechanisms usually require conformational changes, and often there are known structures for the different conformational states. However, usually neither the origin of the driving force nor the underlying pathways for these conformational transitions is known. Exothermic chemical...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Liu, Jie, Sankar, Kannan, Wang, Yuan, Jia, Kejue, Jernigan, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406283/
https://ncbi.nlm.nih.gov/pubmed/28445748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.03.004
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