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Fast-scanning atomic force microscopy reveals the ATP/ADP-dependent conformational changes of GroEL

In order to fold non-native proteins, chaperonin GroEL undergoes numerous conformational changes and GroES binding in the ATP-dependent reaction cycle. We constructed the real-time three-dimensional-observation system at high resolution using a newly developed fast-scanning atomic force microscope....

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Detalhes bibliográficos
Main Authors: Yokokawa, Masatoshi, Wada, Chieko, Ando, Toshio, Sakai, Nobuaki, Yagi, Akira, Yoshimura, Shige H, Takeyasu, Kunio
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1590003/
https://ncbi.nlm.nih.gov/pubmed/16977315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601326
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