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Prostaglandin E2 produced following infection with Theiler's virus promotes the pathogenesis of demyelinating disease

Infection of various cells with Theiler’s murine encephalomyelitis virus (TMEV) activates the TLR- and melanoma differentiation-associated gene 5 (MDA5)-dependent pathways, resulting in the production of IL-1β via the activation of caspase-1 upon assembly of the node-like receptor protein 3 (NLRP3)...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Kim, Seung Jae, Jin, Young-Hee, Kim, Byung S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406002/
https://ncbi.nlm.nih.gov/pubmed/28445497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176406
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