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Prostaglandin E2 produced following infection with Theiler's virus promotes the pathogenesis of demyelinating disease
Infection of various cells with Theiler’s murine encephalomyelitis virus (TMEV) activates the TLR- and melanoma differentiation-associated gene 5 (MDA5)-dependent pathways, resulting in the production of IL-1β via the activation of caspase-1 upon assembly of the node-like receptor protein 3 (NLRP3)...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406002/ https://ncbi.nlm.nih.gov/pubmed/28445497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176406 |
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