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Melanoma Differentiation-Associated Gene 5 Is Critical for Protection against Theiler's Virus-Induced Demyelinating Disease

Infection of dendritic and glial cells with Theiler's murine encephalomyelitis virus (TMEV) induces various cytokines via Toll-like receptor- and melanoma differentiation-associated gene 5 (MDA5)-dependent pathways. However, the involvement and role of MDA5 in cytokine gene activation and the p...

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Bibliografiska uppgifter
Huvudupphovsmän: Jin, Young-Hee, Kim, Seung Jae, So, Eui Young, Meng, Liping, Colonna, Marco, Kim, Byung S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264388/
https://ncbi.nlm.nih.gov/pubmed/22090123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06457-11
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