Transgenic expression of non-structural genes of Theiler’s virus suppresses initial viral replication and pathogenesis of demyelination

BACKGROUND: Chronic infection with Theiler’s murine encephalomyelitis virus (TMEV) in susceptible SJL/J mice induces an immune-mediated demyelinating disease and has extensively been used as a relevant infectious model for multiple sclerosis (MS). Infection of the host with many other viruses also l...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Kang, Hyun Seok, Myoung, Jinjong, So, Eui Young, Bahk, Young Yil, Kim, Byung S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888636/
https://ncbi.nlm.nih.gov/pubmed/27250711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0597-4
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