Pre-leukemic clonal hematopoiesis and the risk of therapy-related myeloid neoplasms: a case-control study

BACKGROUND: Therapy-related myeloid neoplasms (t-MNs) are often fatal secondary malignancies. Risk factors for t-MNs are not well understood. Recent studies suggested that individuals with clonal hematopoiesis have higher risk of developing hematological malignancies. We hypothesized that cancer pat...

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Vydáno v:Lancet Oncol
Hlavní autoři: Takahashi, Koichi, Wang, Feng, Kantarjian, Hagop, Doss, Denaha, Khanna, Kanhav, Thompson, Erika, Zhao, Li, Patel, Keyur, Neelapu, Sattva, Gumbs, Curtis, Bueso-Ramos, Carlos, DiNardo, Courtney D, Colla, Simona, Ravandi, Farhad, Zhang, Jianhua, Huang, Xuelin, Wu, Xifeng, Samaniego, Felipe, Garcia-Manero, Guillermo, Andrew Futreal, P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405697/
https://ncbi.nlm.nih.gov/pubmed/27923552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(16)30626-X
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