RNA processing: a new player of genomic instability in multiple myeloma

Por Marchesini, Matteo, Fiorini, Elena, Colla, Simona
Publicado no Oncoscience (2017)

Dysfunctional telomeres and hematological disorders

Por Fiorini, Elena, Santoni, Andrea, Colla, Simona
Publicado no Differentiation (2018)

CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27(Kip1)-dependent and -independent mechanisms

Por Zhan, Fenghuang, Colla, Simona, Wu, Xiaosong, Chen, Bangzheng, Stewart, James P., Kuehl, W. Michael, Barlogie, Bart, Shaughnessy, John D.
Publicado em 2007

The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells

Por Colla, Simona, Zhan, Fenghuang, Xiong, Wei, Wu, Xiaosong, Xu, Hongwei, Stephens, Owen, Yaccoby, Shmuel, Epstein, Joshua, Barlogie, Bart, Shaughnessy, John D.
Publicado em 2007

Analysis of Class I and II Histone Deacetylase Gene Expression in Human Leukemia

Por Yang, Hui, Maddipoti, Sirisha, Quesada, Andres, Bohannan, Zachary, Calvo, Monica Cabrero, Colla, Simona, Wei, Yue, Estecio, Marcos, Wierda, William, Bueso-Ramos, Carlos, Garcia-Manero, Guillermo
Publicado no Leuk Lymphoma (2015)

LKB1 regulates quiescence and metabolic homeostasis of hematopoietic stem cells

Por Gan, Boyi, Hu, Jian, Jiang, Shan, Liu, Yingchun, Sahin, Ergün, Zhuang, Li, Fletcher-Sananikone, Eliot, Colla, Simona, Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.
Publicado em 2010

Down-regulation of EZH2 expression in myelodysplastic syndromes

Por Cabrero, Monica, Wei, Yue, Yang, Hui, Ganan-Gomez, Irene, Bohannan, Zach, Colla, Simona, Marchesini, Matteo, Bravo, Guillermo Montalban, Takahashi, Koichi, Bueso-Ramos, Carlos, Garcia-Manero, Guillermo
Publicado no Leuk Res (2016)

Constitutive expression of IL-12Rβ2 on human multiple myeloma cells delineates a novel therapeutic target

Por Airoldi, Irma, Cocco, Claudia, Giuliani, Nicola, Ferrarini, Marina, Colla, Simona, Ognio, Emanuela, Taverniti, Giuseppe, Di Carlo, Emma, Cutrona, Giovanna, Perfetti, Vittorio, Rizzoli, Vittorio, Ribatti, Domenico, Pistoia, Vito
Publicado no Blood (2008)

KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice

Por Wei, Yue, Zheng, Hong, Bao, Naran, Jiang, Shan, Bueso-Ramos, Carlos E., Khoury, Joseph, Class, Caleb, Lu, Yue, Lin, Kevin, Yang, Hui, Ganan-Gomez, Irene, Starczynowski, Daniel T., Do, Kim-Anh, Colla, Simona, Garcia-Manero, Guillermo
Publicado no Blood Adv (2018)

Activating somatic and germline TERT promoter variants in myeloid malignancies

Por Nofrini, Valeria, Matteucci, Caterina, Pellanera, Fabrizia, Gorello, Paolo, Di Giacomo, Danika, Lema Fernandez, Anair Graciela, Nardelli, Carlotta, Iannotti, Tamara, Brandimarte, Lucia, Arniani, Silvia, Moretti, Martina, Gili, Alessio, Roti, Giovanni, Di Battista, Valeria, Colla, Simona, Mecucci, Cristina
Publicado no Leukemia (2020)

Downregulation of Protection of Telomeres 1 expression in myelodysplastic syndromes with 7q deletion

Por Cabrero, Monica, Yu, Yiting, Verma, Amit, Yang, Hui, Colla, Simona, Jia, Yu, Zheng, Hong, Bohannan, Zach, Ganan-Gomez, Irene, Futreal, Andrew, Takahashi, Koichi, Chin, Lynda, Kantarjian, Hagop, Pellagatti, Andrea, Bowman, Teresa, Boultwood, Jacqueline, Garcia-Manero, Guillermo, Wei, Yue
Publicado no Br J Haematol (2015)

The molecular classification of multiple myeloma

Por Zhan, Fenghuang, Huang, Yongsheng, Colla, Simona, Stewart, James P., Hanamura, Ichiro, Gupta, Sushil, Epstein, Joshua, Yaccoby, Shmuel, Sawyer, Jeffrey, Burington, Bart, Anaissie, Elias, Hollmig, Klaus, Pineda-Roman, Mauricio, Tricot, Guido, van Rhee, Frits, Walker, Ronald, Zangari, Maurizio, Crowley, John, Barlogie, Bart, Shaughnessy, John D.
Publicado em 2006

Pre-leukemic clonal hematopoiesis and the risk of therapy-related myeloid neoplasms: a case-control study

Por Takahashi, Koichi, Wang, Feng, Kantarjian, Hagop, Doss, Denaha, Khanna, Kanhav, Thompson, Erika, Zhao, Li, Patel, Keyur, Neelapu, Sattva, Gumbs, Curtis, Bueso-Ramos, Carlos, DiNardo, Courtney D, Colla, Simona, Ravandi, Farhad, Zhang, Jianhua, Huang, Xuelin, Wu, Xifeng, Samaniego, Felipe, Garcia-Manero, Guillermo, Andrew Futreal, P.
Publicado no Lancet Oncol (2016)

Impact of Achievement of Complete Cytogenetic Response on Outcome in Patients with Myelodysplastic Syndromes Treated with Hypomethylating Agents

Por Jabbour, Elias, Strati, Paolo, Cabrero, Monica, O’Brien, Susan, Ravandi, Farhad, Bueso-Ramos, Carlos, Wei, Qiao, Hu, Jianhua, Aad, Simon Abi, Short, Nicholas J, Dinardo, Courtney, Daver, Naval, Kadia, Tapan, Wierda, William, Wei, Yue, Colla, Simona, Borthakur, Gautam, Cortes, Jorge, Estrov, Zeev, Kantarjian, Hagop, Garcia-Manero, Guillermo
Publicado no Am J Hematol (2017)

Passenger Deletions Generate Therapeutic Vulnerabilities in Cancer

Por Muller, Florian L., Colla, Simona, Aquilanti, Elisa, Manzo, Veronica, Genovese, Giannicola, Lee, Jaclyn, Eisenson, Dan, Narurkar, Rujuta, Deng, Pingna, Nezi, Luigi, Lee, Michelle, Hu, Baoli, Hu, Jian, Sahin, Ergun, Ong, Derrick, Fletcher-Sananikone, Eliot, Ho, Dennis, Kwong, Lawrence, Brennan, Cameron, Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.
Publicado em 2012

microRNA regulatory network inference identifies miR-34a as a novel regulator of TGFβ signaling in GBM

Por Genovese, Giannicola, Ergun, Ayla, Shukla, Sachet A., Campos, Benito, Hanna, Jason, Ghosh, Papia, Quayle, Steven N., Rai, Kunal, Colla, Simona, Ying, Haoqiang, Wu, Chang-Jiun, Sarkar, Sharmistha, Xiao, Yonghong, Zhang, Jianhua, Zhang, Hailei, Kwong, Lawrence, Dunn, Katherine, Wiedemeyer, Wolf Ruprecht, Brennan, Cameron, Zheng, Hongwu, Rimm, David L., Collins, James J., Chin, Lynda
Publicado em 2012

NPM1 mutations define a specific subgroup of MDS and MDS/MPN patients with favorable outcomes with intensive chemotherapy

Por Montalban-Bravo, Guillermo, Kanagal-Shamanna, Rashmi, Sasaki, Koji, Patel, Keyur, Ganan-Gomez, Irene, Jabbour, Elias, Kadia, Tapan, Ravandi, Farhad, DiNardo, Courtney, Borthakur, Gautham, Takahashi, Koichi, Konopleva, Marina, Komrokji, Rami S., DeZern, Amy, Kuzmanovic, Teodora, Maciejewski, Jaroslaw, Pierce, Sherry, Colla, Simona, Sekeres, Mikkael A., Kantarjian, Hagop, Bueso-Ramos, Carlos, Garcia-Manero, Guillermo
Publicado no Blood Adv (2019)

Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neopl...

Por Montalban-Bravo, Guillermo, Takahashi, Koichi, Patel, Keyur, Wang, Feng, Xingzhi, Song, Nogueras, Graciela M., Huang, Xuelin, Pierola, Ana Alfonso, Jabbour, Elias, Colla, Simona, Gañan-Gomez, Irene, Borthakur, Gautham, Daver, Naval, Estrov, Zeev, Kadia, Tapan, Pemmaraju, Naveen, Ravandi, Farhad, Bueso-Ramos, Carlos, Chamseddine, Ali, Konopleva, Marina, Zhang, Jianhua, Kantarjian, Hagop, Futreal, Andrew, Garcia-Manero, Guillermo
Publicado no Oncotarget (2018)

PAF promotes stemness and radioresistance of glioma stem cells

Por Ong, Derrick Sek Tong, Hu, Baoli, Ho, Yan Wing, Sauvé, Charles-Etienne Gabriel, Bristow, Christopher A., Wang, Qianghu, Multani, Asha S., Chen, Peiwen, Nezi, Luigi, Jiang, Shan, Gorman, Claire Elizabeth, Monasterio, Marta Moreno, Koul, Dimpy, Marchesini, Matteo, Colla, Simona, Jin, Eun-Jung, Sulman, Erik P., Spring, Denise J., Yung, Wai-Kwan Alfred, Verhaak, Roel G. W., Chin, Lynda, Wang, Y. Alan, DePinho, Ronald A.
Publicado no Proc Natl Acad Sci U S A (2017)

Pten is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network

Por Ying, Haoqiang, Elpek, Kutlu G., Vinjamoori, Anant, Zimmerman, Stephanie M., Chu, Gerald C., Yan, Haiyan, Fletcher-Sananikone, Eliot, Zhang, Hailei, Liu, Yingchun, Wang, Wei, Ren, Xiaojia, Zheng, Hongwu, Kimmelman, Alec C., Paik, Ji-hye, Lim, Carol, Perry, Samuel R., Jiang, Shan, Malinn, Brian, Protopopov, Alexei, Colla, Simona, Xiao, Yonghong, Hezel, Aram F., Bardeesy, Nabeel, Turley, Shannon J., Wang, Y. Alan, Chin, Lynda, Thayer, Sarah P., DePinho, Ronald A.
Publicado em 2011