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Formation of A Novel Purine Metabolite through CYP3A4 Bioactivation and Glutathione Conjugation
BACKGROUND: The study of novel sites of metabolism is important in understanding new mechanisms of biotransformation of a particular moiety by metabolic enzymes. This information is valuable in designing metabolically-stable compounds with drug-like properties. It may also provide insights into the...
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| Publicado no: | Drug Metab Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5405620/ https://ncbi.nlm.nih.gov/pubmed/27165340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1872312810666160511150558 |
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