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Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes
BACKGROUND: Berberine (BBR) is a drug with multiple effects on cellular energy metabolism. The present study explored answers to the question of which CYP450 (Cytochrome P450) isoenzymes execute the phase-I transformation for BBR, and what are the bioactivities of its metabolites on energy pathways....
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Päätekijät: | , , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
BioMed Central
2011
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103436/ https://ncbi.nlm.nih.gov/pubmed/21569619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-62 |
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