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Context dependent effects of amplified MAPK signaling during lung adenocarcinoma initiation and progression
Expression of oncogenic Kras(G12D) initiates lung adenomas in a MAPK signal-dependent manner from only a subset of cell types in the adult mouse lung. Amplification of MAPK signaling is associated with progression to malignant adenocarcinomas, but whether this is a cause or consequence of disease pr...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5405440/ https://ncbi.nlm.nih.gov/pubmed/28228261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.01.069 |
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