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RB constrains lineage fidelity and multiple stages of tumour progression and metastasis
Mutations in the Retinoblastoma (RB) tumour suppressor pathway are a hallmark of cancer and a prevalent feature of lung adenocarcinoma(1,2,3). Despite being the first tumour suppressor to be identified, the molecular and cellular basis underlying selection for persistent RB loss in cancer remains un...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522292/ https://ncbi.nlm.nih.gov/pubmed/31043741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1172-9 |
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