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Structural and biochemical characterization of the nucleoside hydrolase from C . elegans reveals the role of two active site cysteine residues in catalysis

Nucleoside hydrolases (NHs) catalyze the hydrolysis of the N‐glycoside bond in ribonucleosides and are found in all three domains of life. Although in parasitic protozoa a role in purine salvage has been well established, their precise function in bacteria and higher eukaryotes is still largely unkn...

詳細記述

保存先:
書誌詳細
出版年:Protein Sci
主要な著者: Singh, Ranjan Kumar, Steyaert, Jan, Versées, Wim
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405431/
https://ncbi.nlm.nih.gov/pubmed/28218438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3141
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