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Alternative RNA splicing: contribution to pain and potential therapeutic strategy

Since the sequencing of metazoan genomes began, it has become clear that the number of expressed proteins far exceeds the number of genes. It is now estimated that more than 98% of human genes give rise to multiple proteins through alternative pre-mRNA splicing. In this review, we highlight the know...

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Publicat a:Drug Discov Today
Autors principals: Donaldson, Lucy F., Beazley-Long, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405051/
https://ncbi.nlm.nih.gov/pubmed/27329269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2016.06.017
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