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Alternative RNA splicing: contribution to pain and potential therapeutic strategy
Since the sequencing of metazoan genomes began, it has become clear that the number of expressed proteins far exceeds the number of genes. It is now estimated that more than 98% of human genes give rise to multiple proteins through alternative pre-mRNA splicing. In this review, we highlight the know...
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Publicado no: | Drug Discov Today |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5405051/ https://ncbi.nlm.nih.gov/pubmed/27329269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2016.06.017 |
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